Need help with my Samsung LED TV

Either a bad cable/interference or a bad board/input on the TV itself

I remember seeing your setup, how long is the HDMI cable run? Have you added anything new since the initial setup?

The fact that its not saving the setting is why I am suspicious of it being a bad board… Will it save other changed settings?

Try putting the cable in a different input on the TV, also try using another device, narrow it down