Absolutely. You put a good driver in anything and they will do fine.
I grew up with FWD and a shift on the fly Durango. I can handle a FWD pretty well and with my new dunlops, I doubt I will have many problem. The stock Toyos on my 3 were okay once moving, but getting going was tricky sometimes.
The Durango would be tricky in 2WD going up a hill and I would have to swich to 4WD to get up hills and what not. Then again, I haven’t been trained on RWD as much and could probably do better if I only had a RWD to get around in…