why not? compression is only half the battle, GI-JOE!!!
less boost, more flow (bigger turbo(s)) + higher flash point fuel divided by high compression = OK
MOAR boost, more flow (bigger turbo(s)) - higher flash point fuel divided by high compression = :ohnoes
and there is allways timing to consider of course.
many guys in the vw world are going higher compression with race fuel/e85 on the same frame turbos and making more power than before, and safely.