It really depends on the car then, I guess. Normal driving might (and should) be fine if the o2 sensors are ok, but the P.E. fueling curve isn’t affected by temperature changes. Doing WOT blasts down the highway in the middle of winter on a summer tune is a race against time (and a melted piston or two).
The reason I say that is because (for example) a car that’s commanding an 11.7:1 AFR at WOT may be OK in the summertime and not experience any knock or lean symptoms, but in the winter the cylinder airmass is a lot more dense. You really need to add fuel to the wot tables in order to be safe in the cold weather.
Running lean up top when it’s cold is never a good thing, lol.