I would guestimate that the JSF or some variant based on it will take over the F117’s role. The F117 while it was a cool aircraft, was very limited in capability, and was not as efficient compared to other aircraft on dropping quanity of ordinance per sortie. Honestly, the JSF in it’s stock form already can match or outperform the F117, and costs a lot less money.
I doubt the F22 will be used to replace the Nighthawk’s role just because it is too specialized as an air superiority aircraft by design. That’s just my opinion though. I’ve been out of the loop for a while.
97FormulaWS-6 pretty much covered everything else.