Tps sensor could just need adjusting, knock sensor code isn’t a huge deal but is ssomething that’s an easy fix, and the code 22 means your vtec isn’t working… So yes I’d fix them all
This isn’t always a bad sensor issue. Something like a bad ground or wiring harness short could cause the above symptoms.
If I were you, I would get the factory service manual and follow the troubleshooting steps for each code. This will help you narrow down the cause of the codes.