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VQ will blow up first just like a KA will blow up first. Neither are built for boost. They both have Cast Aluminum pistons and small, weak wrist pins.
A VG30DETT can see 800WHP and run all day on stock boosted internals where a VQ35DETT can probably run a little more than 550WHP on boosted stock internals. Its just harder and more expensive to get the VG30DETT up to 550WHP.

It’s just the evolution of the airflow pattern that makes it a better engine to boost. Don’t quote me on this, but I believe the bottom end is pretty much the same as the VG but the VQ has an all aluminum block.