you should if you use just regular #2. the sulfur content of on road diesel isnt as high as it used to be, and sulfur = lubrication.
i run B5 biodiesel from John Ray in Troy. no additive needed due to the bio agents that supply added lubricant to the fuel.
stanadyne is amazing stuff, but you can just get a measuring bottle, and buy the power service(white bottle) and measure out about 8 ounces to a tank and dump it in.